Potential cellular and biochemical mechanisms of exercise and physical activity on the ageing process

  • Mark Ross
  • , Hannah Lithgow
  • , Lawrence Hayes
  • , Geraint Florida-James

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Exercise in young adults has been consistently shown to improve various aspects of physiological and psychological health but we are now realising the potential benefits of exercise with advancing age. Specifically, exercise improves cardiovascular, musculoskeletal, and metabolic health through reductions in oxidative stress, chronic low-grade inflammation and modulating cellular processes within a variety of tissues. In this this chapter we will discuss the effects of acute and chronic exercise on these processes and conditions in an ageing population, and how physical activity affects our vasculature, skeletal muscle function, our immune system, and cardiometabolic risk in older adults.
Original languageEnglish
Title of host publicationBiochemistry and cell biology of ageing: part II clinical science
EditorsViktor I. Korolchuk, J. Robin Harris
Place of PublicationSingapore
PublisherSpringer
Pages311-338
Volume91
ISBN (Print)9789811336805
DOIs
Publication statusPublished - 1 Jan 2019

Keywords

  • ageing
  • exercise
  • physical activity
  • cardiovascular disease
  • endothelial function
  • tissue regeneration
  • skeletal muscle
  • atrophy
  • sarcopenia
  • insulin resistance
  • immunology
  • bone health
  • oxidative stress

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