Towards structurally new cyanine dyes: investigating the photophysical and potential antifungal properties of linear substituted heptamethine dyes

Okoh Adeyi Okoh; Clare L. Lawrence; Roger H. Bisby; Samuel Lewis Brennan; Robert B. Smith

doi:10.1111/cote.12780

Towards structurally new cyanine dyes: investigating the photophysical and potential antifungal properties of linear substituted heptamethine dyes

Okoh Adeyi Okoh
, Clare L. Lawrence
, Roger H. Bisby
, Samuel Lewis Brennan
, Robert B. Smith

University of Central Lancashire
University of Salford

Research output: Contribution to journal › Journal Article › peer-review

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Abstract

The synthesis of a range of new linear substituted heptamethine dyes has been designed and described. The photophysical properties of all the dyes were investigated, with many exhibiting improved fluorescent quantum yields when compared with indocyanine green. Finally, growth inhibition studies were performed in the fission yeast Saccharomyces pombe, which suggests potential antifungals activity in the μM range.

Original language	English
Pages (from-to)	20-25
Number of pages	6
Journal	Coloration Technology
Volume	141
Issue number	1
Early online date	4 Jul 2024
DOIs	https://doi.org/10.1111/cote.12780
Publication status	Published - 1 Feb 2025

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abstract = "The synthesis of a range of new linear substituted heptamethine dyes has been designed and described. The photophysical properties of all the dyes were investigated, with many exhibiting improved fluorescent quantum yields when compared with indocyanine green. Finally, growth inhibition studies were performed in the fission yeast Saccharomyces pombe, which suggests potential antifungals activity in the μM range.",

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AU - Smith, Robert B.

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AB - The synthesis of a range of new linear substituted heptamethine dyes has been designed and described. The photophysical properties of all the dyes were investigated, with many exhibiting improved fluorescent quantum yields when compared with indocyanine green. Finally, growth inhibition studies were performed in the fission yeast Saccharomyces pombe, which suggests potential antifungals activity in the μM range.

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Towards structurally new cyanine dyes: investigating the photophysical and potential antifungal properties of linear substituted heptamethine dyes

Abstract

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